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Faulty cable, broken solder joint, or corrupted driver stack. Solution: Try a different USB port (USB 2.0 preferred, not USB 3.0). Uninstall all USB drivers and let Windows redetect.
If you want, I can:
Not all KKL 409.1 cables are the same inside. Your installation path depends entirely on the USB-to-Serial chip used: FTDI (FT232RL or FT232BL) vag kkl 409.1 driver windows 10 64 bit