The 64-bit executable (added in a 2019 update) is a significant improvement over the original 32-bit version, especially on modern PCs.
Some users report that the 64-bit client has trouble with PlayStation controllers (DS4/DualSense) via Steam Input. borderlands 2 64 bit
While Gearbox Software never released a native 64-bit executable for Windows, the situation is different for other platforms. In 2019, as part of the "Ultra HD Texture Pack" update, the macOS version of Borderlands 2 was updated to 64-bit to maintain compatibility with newer versions of macOS that dropped 32-bit support entirely. Linux users also have various workarounds, but the Windows community remains on the original architecture. The 64-bit executable (added in a 2019 update)